Quinoa starch microspheres for drug delivery: preparation and their characteristics

2 Microspheres for Drug Delivery

Development of Biodegradable Starch Microspheres for Intranasal Delivery

Domperidone microspheres for intranasal administration were prepared by emulsification crosslinking technique. Starch a biodegradable polymer was used in preparation of microspheres using epichlorhydrine as cross-linking agent. The formulation variables were drug concentration and polymer concentration and batch of drug free microsphere was prepared for comparisons. All the formulations were ev...

Bioadhesive Microspheres for Tuberculosis Drug Delivery

Tuberculosis (TB) is an infectious disease that mainly affects the lungs. For the treatment of tuberculosis, conventional drug delivery system fails to achieve efficient drug delivery system fails to achieve efficient drug delivery at the target site. Today, bioadhesive microspheres became a topic of great interest as a novel carrier for drug delivery. Bioadhesive microspheres offers longer ret...

Preparation, evaluation and bioavailability studies of Indomethacin loaded PEA polymeric microspheres for controlled drug delivery

The goal of any drug delivery system is to provide a therapeutic amount of drug (s) to the proper site in the body in order to promptly achieve and thereby to maintain the desired drug concentrations during treatment. This idealized objective can be achieved by targeting the drugs to a specific organ or tissue with the help of controlling the release rate of the drug during the transit time in ...

Hollow microspheres for gastroretentive floating- pulsatile drug delivery: preparation and in vitro evaluation.

PURPOSE A multiparticular floating-pulsatile drug delivery system was developed for time and site specific drug release of piroxicam. A blend of floating and pulsatile principles of drug delivery system would have the advantage that a drug can be released in the upper GI tract after a definite time period. METHODS Hollow microspheres were prepared by the emulsion solvent diffusion method usin...